physician photo

H. Henry Lai, MD

  • Associate Professor of Surgery (Urology)
  • Associate Professor of Anesthesiology

Medical School

Cornell University Medical College, New York, NY, 1999.

Post Doctoral Education

Internship: Baylor College of Medicine, Houston, TX, 1999-2000.

Residency: Baylor College of Medicine, Houston, TX, 2000-2005.

Fellowship: Neurourology, Urodynamics and Female Urology, Baylor College of Medicine, Houston, TX, 2005-2007.

Board Certifications

Female Pelvic Medicine & Reconstructive Surgery--Certified


Honors and Awards

2005: American Urologic Association Foundation Research Scholar

2004: International Jack Lapides Essay Contest on Neurourology and Urodynamics, Second Prize

2003 & 2005: Cullen Research Award for Outstanding Research in Urology, Baylor College of Medicine, Houston, TX

1999: Elected to Alpha Omega Alpha (AOA) Medical Honor Society

1997: Howard Hughes Medical Institute-NIH Research Scholar

1994: Barry Goldwater Scholar in Mathematics, Science and Engineering

Clinical Interests

Dr. Lai’s areas of expertise include urology, urinary incontinence in males and females, overactive bladder, female urology, vaginal prolapse (cystocele, post-hysterectomy vaginal vault prolapse), enlarged prostate, neurogenic bladder, stress urinary incontinence, female urology conditions, benign prostatic hyperplasia, neurogenic bladder, artificial urinary sphincter, neuromodulation (Interstim) and Botox treatment of incontinence.

Patients Seen At

Center for Advanced Medicine
Urologic Surgery Center
4921 Parkview Place, Suite C, Floor 11
St. Louis, MO 63110
(314) 362-8200
Fax (314)-454-5244

Selected Publications

You may get the most updated list using a PubMed search.

Lai HH, Hsu EI, Teh BS, Butler EB, Boone TB. Thirteen years of experience with artificial urinary sphincter implantation at Baylor College of Medicine. Journal of Urology. 2007;177(3):1021-1025.

Lai HH, Boone TB, Thompson TC, Smith CP, Somogyi GT. Using caveolin-1 knockout mouse to study impaired detrusor contractility and disrupted muscarinic activity in the aging bladder. Urology. 2007;69(2):407-411.

Lai HH. The diagnosis and medical treatments of female overactive bladder and painful bladder syndrome. Urol Rep. 2007;1(1):23-32.

Lai HH, Smith CP. Hitting below the belt (bladder): Botulinum toxin treatment of urethral and prostate disorders. Curr Urol Rep. (in press, 2007)

Lai HH, Simon M, Boone TB. The impact of detrusor overactivity on the management of stress urinary incontinence in women. Curr Urol Rep. 2006;7(5):354-362.

Smith PP, Lai HH, Appell RA. Darifenacin. Selective M3 muscarinic receptor antagonist for the treatment of overactive bladder. Therapy. 2006;3(6):723-732.

Lai HH, Boone TB, Smith CP, Yang G, Kiss S, Thompson TC, Somogyi GT. Loss of caveolin-1 expression is associated with disruptions of muscarinic cholinergic activities in the urinary bladder. Neurochemistry International. 2004;45(8):1185-1193.

Lai HH, Boone TB, Appell RA. Pharmacologic treatment for detrusor overactivity. Curr Urol Rep. 2002;3(5):365-372.

Lai HH, Boone TB, Appell RA. Selecting a medical therapy for overactive bladder. Rev Urology. 2002;4(supp 4):S28-S37.

Ascheim DD, Markowitz SM, Lai HH, Engelstein ED, Stein KM, Lerman BB. Vasodepressor syncope due to subclinical myocardial ischemia. Journal of Cardiovascular Electrophysiology. 1997;8(2):215-221.

Lai HH, Li T, Lyons DS, Phillips GN Jr, Olson JS, Gibson QH. Phenylalanine-46 orients the distal histidine for hydrogen bonding to bound ligands in sperm whale myoglobin. Proteins (US). 1995;22(4):322-339.


Lai HH, Gross M, Boone TB, Appell RA. Pharmacologic and surgical management of detrusor instability. In: Vasavada SP et al. (eds.) Female Urology and Urogynecology. New York: Marcel Dekker; 2005:191-214.

Lai HH, Smith CP, Boone TB. Urodynamics evaluation. In: Raz and Rodriguez (eds.). Female Urology (3rd edition). Philadelphia: W.B. Saunders; in press.

Lai HH, Boone TB. Urinary incontinence in women. In: Lipshultz LI and Khera M (eds.). Urology and the Primary Care Practitioner (2nd Edition). London: Mosby-Wolfe; in press.